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Camacho honored by NIH for research on emotional neurodevelopment

Neuroscientist selected for High-Risk, High-Reward program

by Kristina SauerweinOctober 8, 2024

Cat CamachoPhoto courtesy of Camacho

Maria Catalina Camacho, PhD, an assistant professor in the Department of Psychiatry at Washington University School of Medicine in St. Louis, has received the NIH Director’s Early Independence Award, part of the National Institutes of Health (NIH) High-Risk, High-Reward Research program.

This year, the award provides $1.25 million over five years to, according to the NIH, “promising, newly graduated scientists with the intellect, scientific creativity, drive and maturity” to take an accelerated path to an independent research career. Around 10 scholars are selected for this opportunity annually.

Camacho’s research focuses on how the human brain makes sense of a person’s social and emotional worlds, with the goal of better understanding the neurobiological underpinnings that place some children at risk for developing anxiety or depressive symptoms.

The grant will help fund a study that will test a computational model of how early experiences shape emotional neurodevelopment. To build such a model, Camacho’s lab will collect data from 3- and 4-year-old children. “By doing this, we can test hypotheses about how early social experiences shape our brains to learn how to understand emotions,” Camacho said. “We think that early emotional neurodevelopment can set up a child to be more or less vulnerable to developing anxiety or depressive symptoms later in life, so this is an important basic scientific step to understanding how depression and anxiety emerge.”

“I am so excited by this study,” Camacho said. “I’ve always been motivated to study anxiety and depression by, unfortunately, the many loved ones in my life who have struggled with these symptoms, especially the negative social consequences of them. Depression and anxiety commonly co-occur but have distinct features. I and many others think that identifying the developmental and neuroscientific basis will make it easier to identify children at risk and potentially inform intervention and treatment.”

Chad M. Sylvester, MD, PhD, an associate professor of psychiatry at WashU Medicine who has mentored Camacho, said she “is a superstar who is incredibly deserving of this highly competitive early-career award. She is the whole package: Dr. Camacho has groundbreaking ideas; she is a gifted communicator; she is a tireless and highly dedicated mentor; and she is an amazing colleague and collaborator. I cannot wait to see the incredible science that she produces.”

Camacho earned a bachelor’s degree with honors in psychology in 2014 from Stanford University in Palo Alto, Calif., and her doctorate in neuroscience in 2022 from WashU Medicine’s Division of Biology & Biomedical Sciences under Deanna M. Barch, PhD, vice dean of research and a professor of psychological & brain sciences in Arts & Sciences, and the Gregory B. Couch Professor of Psychiatry. Camacho is continuing her research at WashU Medicine.

About Washington University School of Medicine

WashU Medicine is a global leader in academic medicine, including biomedical research, patient care and educational programs with 2,900 faculty. Its National Institutes of Health (NIH) research funding portfolio is the second largest among U.S. medical schools and has grown 56% in the last seven years. Together with institutional investment, WashU Medicine commits well over $1 billion annually to basic and clinical research innovation and training. Its faculty practice is consistently within the top five in the country, with more than 1,900 faculty physicians practicing at 130 locations and who are also the medical staffs of Barnes-Jewish and St. Louis Children’s hospitals of BJC HealthCare. WashU Medicine has a storied history in MD/PhD training, recently dedicated $100 million to scholarships and curriculum renewal for its medical students, and is home to top-notch training programs in every medical subspecialty as well as physical therapy, occupational therapy, and audiology and communications sciences.

Kristina covers pediatrics, surgery, medical education and student life. In 2020, she received a gold Robert G. Fenley Writing Award for general staff writing from the Association of American Medical Colleges (AAMC), and in 2019, she received the silver award. Kristina is an author and former reporter for the St. Louis Post-Dispatch and the Los Angeles Times, where she was part of a team of journalists that won the Pulitzer Prize in 2004 for breaking news. Additionally, she covered the 2014 Ferguson unrest for TIME magazine and, for eight years, wrote a popular parenting column for BabyCenter.com.