Everyone knows cancer. Few understand it like we do.
Impact
At the forefront of discovery in cancer care, WashU Medicine researchers at Siteman Cancer Center are accelerating bold discoveries and delivering breakthroughs where they matter most: our patients’ bedsides. Our world-class teams are leading a new era in detection, treatment and prevention to outpace cancer on every front. Because the better we understand cancer, the closer we get to a world where no one has to know it.
Cancer by the numbers

Siteman Cancer Center is top six nationally in patient volume

100,000+ patients cared for annually

600+ active treatment clinical trials

$160+M in current research funding
Vaccine offers hope against an incurable brain cancer
One of the deadliest brain cancers, glioblastoma grows quickly and resists treatment. WashU Medicine researchers are on a mission to change that. We developed a first-of-its-kind, personalized vaccine that helps the immune system recognize and attack each patient’s unique tumor proteins — significantly prolonging survival in an early-stage clinical trial.
New blood cancer treatment on the fast track to rewriting patients’ futures
A cell-based immunotherapy developed by WashU Medicine researchers has received Breakthrough Therapy designation from the FDA — accelerating its development as a potentially lifesaving treatment for rare and aggressive types of blood cancer.
The future of breast cancer prevention is here
A new AI-based imaging technology can predict a patient’s future breast cancer risk by analyzing subtle patterns in a standard mammogram. Developed by WashU Medicine researchers and recently acquired by a leading medical AI company, this tool promises to save more lives through earlier, more personalized prevention.
How to catch a killer, sooner
A person’s risk of blood cancer is shaped by a complex interplay between inherited genetics and mutations acquired over a lifetime. New research reveals how mutations in blood stem cells — driven by factors like smoking, toxins or aging — interact with inherited variants, ultimately amplifying or mitigating lifetime risk. This pivotal discovery opens new avenues for early detection and prevention.
Confronting the alarming rise of colorectal cancer in adults under 50
For years, Michael Rall-Brown managed chronic digestive issues without realizing they signaled something more serious. When sudden, severe pain sent him to the ER, WashU Medicine doctors discovered hundreds of polyps and a genetic mutation linked to early-onset colorectal cancer. His life-saving surgery underscored a troubling trend: colorectal cancer is rising in adults under 50, often going undetected until it’s advanced. Why are cases surging, and how can early action save lives?
Outsmarting cancer with precision medicine
What began as a bold, untested idea — sequencing an entire cancer genome — became a breakthrough that changed medicine forever. Now, 15 years later, WashU Medicine physicians at Siteman Cancer Center continue to push the limits of what’s possible, using cutting-edge genetic tests to outsmart cancer and save more lives.
Discover the latest innovations in cancer prevention, research and care in our recent issue of Outlook Magazine »
Meet Siteman Cancer Center’s 10,000th stem cell transplant patient
A breakthrough in blood cancer: gene-altering treatment offers new hope





