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Everyone knows cancer. Few understand it like we do.

At the forefront of discovery in cancer care, WashU Medicine researchers at Siteman Cancer Center are accelerating bold discoveries and delivering breakthroughs where they matter most: our patients’ bedsides. Our world-class teams are leading a new era in detection, treatment and prevention to outpace cancer on every front. Because the better we understand cancer, the closer we get to a world where no one has to know it. 

Cancer by the numbers

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Siteman Cancer Center is top six nationally in patient volume  

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100,000+ patients cared for annually  

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600+ active treatment clinical trials

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$160+M in current research funding

Researcher studying brain scans. Links to full story.

One of the deadliest brain cancers, glioblastoma grows quickly and resists treatment. WashU Medicine researchers are on a mission to change that. We developed a first-of-its-kind, personalized vaccine that helps the immune system recognize and attack each patient’s unique tumor proteins — significantly prolonging survival in an early-stage clinical trial. 

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A cell-based immunotherapy developed by WashU Medicine researchers has received Breakthrough Therapy designation from the FDA — accelerating its development as a potentially lifesaving treatment for rare and aggressive types of blood cancer.

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Researchers in the CORTEX. Links to full story.
links to the prognosia story

A new AI-based imaging technology can predict a patient’s future breast cancer risk by analyzing subtle patterns in a standard mammogram. Developed by WashU Medicine researchers and recently acquired by a leading medical AI company, this tool promises to save more lives through earlier, more personalized prevention.  

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A person’s risk of blood cancer is shaped by a complex interplay between inherited genetics and mutations acquired over a lifetime. New research reveals how mutations in blood stem cells — driven by factors like smoking, toxins or aging — interact with inherited variants, ultimately amplifying or mitigating lifetime risk. This pivotal discovery opens new avenues for early detection and prevention.

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links to the blood cancer story
links to colorectal cancer story

For years, Michael Rall-Brown managed chronic digestive issues without realizing they signaled something more serious. When sudden, severe pain sent him to the ER, WashU Medicine doctors discovered hundreds of polyps and a genetic mutation linked to early-onset colorectal cancer. His life-saving surgery underscored a troubling trend: colorectal cancer is rising in adults under 50, often going undetected until it’s advanced. Why are cases surging, and how can early action save lives?

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What began as a bold, untested idea — sequencing an entire cancer genome — became a breakthrough that changed medicine forever. Now, 15 years later, WashU Medicine physicians at Siteman Cancer Center continue to push the limits of what’s possible, using cutting-edge genetic tests to outsmart cancer and save more lives. 

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links to Precision Medicine story

Discover the latest innovations in cancer prevention, research and care in our recent issue of Outlook Magazine »


Meet Siteman Cancer Center’s 10,000th stem cell transplant patient

A breakthrough in blood cancer: gene-altering treatment offers new hope


Stay informed with the latest news in cancer research and care